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Assessment of Biogenic Amines

The concentrations of catecholamines may be determined in serum, plasma, urine, other body fluids and even cell culture supernatants. The most commonly used methodology is HPLC combined with electrochemical detection.However this methodology is subject to analytical error, when synthetic sympatho-mimetic therapeutic agents, in comparatively high concentrations present, interfere with the quantitative determination of endogenous catecholamines. Peaks arriving from these synthetic agents will mask the biogenic amine peaks , making exact determinations almost impossible. An alternative and more specific method for the determination of biogenic amines in any type of sample is immuno-assay , whether as radioimmunoassay (RIA) or enzyme immunoassay (ELISA)

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CLOSING DAYS 2019 : 1/01-22/04-01&30/05-10/06-21/07-15/08-01&11/11-25/12

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