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Follicle Stimulating Hormone (FSH)

The measurement of LH and FSH concentrations in serum is essential for investigating fertility and especially disorders of the hypothalamic/pituitary/gonadal axis. Both LH and FSH are secreted by the basophil cells of the anterior pituitary as a result of gonadotropin releasing hormone (GnRH) secretion from hypothalamic cells. In adults, LH and FSH hormones control gonadal functions; mainly gametogenesis and steroid secretion. Circulating levels of FSH are controlled by a negative feedback effect on the hypothalamus by steroidal hormones and gonadal peptides.


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